![]() Earlier studies have shown that the combination of Cr Pic and biotin improves glycemic control, lipid profiles, and enhances glucose uptake and glycogen synthesis in skeletal muscle cells. All rights reserved.Improvement in Fasting Blood Glucose with the Combination of Chromium Picolinate and Biotin in Type 2 Diabetes Mellitus Chromium picolinate (Cr Pic) i Chromium picolinate (Cr Pic) improves insulin sensitivity and biotin improves beta cell function leading to enhancement of insulin regulation. The results of the current meta-analysis study might support the use of chromium supplementation for the improvement of glycemic control indices in T2DM patients.Ĭhromium clinical trials diabetes glycemic control meta-analysis.Ĭopyright © 2020 Elsevier Ltd. Twenty-eight studies reported fasting plasma glucose (FPG), insulin, hemoglobin A1C (HbA1C) and homeostatic model assessment for insulin resistance (HOMA-IR) as an outcome measure. Mean change and standard deviation (SD) of the outcome measures were used to estimate the mean difference between the supplementation group and the control group at follow-up. Randomized controlled trials examining the effect of chromium supplementation on glycemic control indices and published before February 2020 were detected by searching online databases, including PubMed, Scopus, Embase, Web of sciences and The Cochrane Library, using a combination of suitable keywords. Electronic address: aimed to investigate the effect of chromium supplementation on glycemic control indices in patients with type 2 diabetes (T2DM). Electronic address: 8 Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: 7 Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: 6 Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. ![]() Electronic address: 5 Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: 4 Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Students Scientific Research Center (SSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran. Electronic address: 3 Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. ![]() Electronic address: 2 Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Science, Tehran, Iran. Electronic address: 1 Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran. ![]()
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